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1. Patient A. 65 years old complains of weakness, sweating, weight loss by 12 kg in 2 years.Objectively: hepatosplenomegaly, lymphadenopathy. In UAC - er.- 3,0x1012/l, NV – 85g/l, lake.- 135x109/l, p- 3%, lymph.-96%, m-1%, Botkin-Gumprecht shadows, ESR- 32 mm/hour. Choose the most likely diagnosis?

1) Acute leukemia
2) Chronic lymphocytic leukemia
3) Chronic myeloid leukemia
4) Lymphosarcoma
5) Myelofibrosis

2. Patient S., 45 years old - complaints of weakness, weight loss, dull pains in the left hypochondrium. Objectively: the skin is pale, the lymph nodes are not enlarged. The liver is 3 cm below the costal arch, the spleen is at the navel level, dense, painless. In the UAC:- er.-3.0x1012/l, leukocytes- 96x109/l, myeloblasts-2%, promyelocytes-4%, metamyelocytes-8%, pal.-2%, c- 52%,e-9%,b-11%,l-12%, t R.-200x109/l, SOE- 56 mm/h Choose the most likely diagnosis:

1) Chronic myeloid leukemia
2) Chronic lymphocytic leukemia
3) Erythremia
4) Leukemoid reaction of myeloid type
5) Acute myeloblastic leukemia

3. The cause of increased bleeding in diseases of the blood and hematopoiesis:

1) scratching, itching of the skin
2) iron deficiency in the body
3) iron deficiency in the body, vascular wall changes
4) platelet reduction
5) destruction of the vessel wall

4. Puncture used in blood pathology:

1) There is no correct answer
2) Pleural
3) Abdominal
4) Lumbar
5) Sternal

5. Poikilocytosis is a change in red blood cells according to:

1) value
2) mobility
3) diameter
4) form
5) coloring

6. The patient is 65 years old, lymphadenopathy. B blood test – leukocytosis with absolute lymphocytosis, Botkin's shadow - Gumprecht Your diagnosis:

1) lymphogranulomatosis
2) lymphosarcoma
3) myeloma
4) chronic lymphocytic leukemia
5) acute leukemia

7. The most characteristic feature of B12 — deficient anemia is:

1) Change of ESR
2) macrocytosis
3) Erythrocytosis
4) Microcytosis
5) Reduction of the color index

8. Necrotic angina is observed in patients:

1) after bleeding
2) with iron deficiency in the body
3) for leukemia
4) with iron deficiency in the body
5) with increased hemolysis

9. The cause of increased bleeding in diseases of the hematopoietic organs:

1) destruction of the vessel wall
2) iron deficiency in the body
3) iron deficiency in the body, vascular wall changesitamin B12 deficiency in the body
4) scratching, itching of the skin
5) convolution system changes

10. Clotting time increases with:

1) insufficiency of plasma clotting factors
2) insufficiency of all components of hemostasis.
3) iron deficiency in the body
4) vascular wall fragility
5) thrombocytopenia

11. question> A 68-year-old patient complains of weakness, sweating, weight loss by 10 k in 2 years. Enlarged liver, spleen and all groups of lymph nodes. Blood test: Hb – 85 g/l, E-3.0 x 1012/l, leukocytes-135,0x10 9 , P-3%; lymphocytes -96%; monocytes-1%; Botkin-Gumprecht shadows ESR- 28 mm/h.

1) Chronic myeloid leukemia
2) Myelofibrosis
3) Lymphosarcoma
4) Chronic lymphocytic leukemia
5) Acute leukemia

12. An increase in the color index is observed in anemia:

1) posthemorrhagic
2) iron deficiency
3) aplastic
4) B12 deficient
5) hemolytic

13. In chronic myeloid leukemia , the following signs are noted:

1) Jolly's corpuscles and Cabot's rings in blood smears
2) Botkin –Gumprecht shadows in blood smears
3) during karyological examination, the presence of a Ph' chromosome
4) anisocytosis, poikilocytosis
5) leukocytosis with absolute lymphocytosis

14. Myeloproliferative diseases include

1) chronic lymphocytic leukemia
2) chronic myeloid leukemia
3) lymphogranulomatosis
4) thrombocytopenia
5) myeloma

15. Syndrome characteristic of chronic leukemia:

1) gastric dyspepsia
2) intestinal dyspepsia
3) of cytolysis
4) proliferative
5) liver failure

16. Name a characteristic symptom of B12 deficiency anemia:

1) fever
2) Enlargement of lymph nodes
3) pallor of mucous membranes
4) Funicular myelosis
5) perversion of taste

17. With regard to lymphadenopathy in chronic lymphocytic leukemia , it is true:

1) the formation of fistulas during suppuration is characteristic
2) palpation of lymph nodes is painful
3) lymph nodes are painless during palpation
4) rocky density lymph nodes
5) the lymph nodes are soldered together and the surrounding tissue

18. Specify the blood picture for B12 — deficient anemia:

1) Microcytosis
2) Change of ESR
3) Increasing the color index
4) of Red blood cells
5) Reduction of the color index

19. The most likely cause of B12-deficiency anemia is:

1) donation
2) metrorrhagia
3) hemorrhoids
4) ionizing radiation
5) Castle's internal factor deficiency

20. The diagnosis of chronic lymphocytic leukemia corresponds to:

1) blastemia
2) during karyological examination, the presence of a Ph' chromosome
3) infectious complications are rare
4) there are Botkin–Gumprecht shadows in the blood smears
5) the disease is most often observed at a young age

21. Factors predisposing to the development of pathology of the hematopoietic system:

1) x-rays
2) physical inactivity
3) overheating
4) nervous overstrain
5) hypothermia

22. Complaints of patients with hematopoietic pathology:

1) burning tongue, bone pain
2) heartburn, epigastric pain
3) weight gain
4) suffocation attacks
5) sleep disturbance

23. Examination of the skin and visible mucous membranes of patients with pathology of the hematopoietic system reveals:

1) acrocyanosis
2) cyanotic blush
3) hyperpigmentation areas
4) hemorrhages
5) diffuse cyanosis

24. Examination of patients reveals

1) Stelvag's symptom
2) pallor of the skin, cracks in the corners of the mouth+
3) musset's symptom
4) dry skin, puffiness
5) facial hyperemia, eye shine

25. < The main complaints of patients with pathology of hematopoiesis

1) increased appetite
2) nickturia
3) frequent urination
4) decreased appetite, increased body temperature
5) weight loss, heartbeat

26. Factors contributing to the development of anemic syndrome

1) lack of sleep, overwork
2) heredity
3) edema, trophic disorders on the legs
4) blood loss, malnutrition
5) hypothermia, overheating

27. The main complaints of patients with anemic syndrome

1) weakness, increased body temperature
2) weight gain
3) dizziness, headache
4) suffocation attacks
5) shortness of breath, cough

28. The main complaints of patients with pathology of hematopoiesis

1) increased appetite
2) increase in body temperature
3) decreased appetite
4) weight loss
5) frequent urination

29. Blood from a vein is taken to determine the blood group and Rh factors:

1) At any time of the day, in a clean, centrifuge tube, 8-10 ml
2) In the morning, on an empty stomach, in a clean, dry, centrifuge tube with an anticoagulant, 8-10 ml
3) In the evening, after dinner, 10-20 ml
4) In the morning, on an empty stomach, from a vein, into a clean, dry, centrifuge tube, 8-10 ml
5) There is no correct answer

30. Oxygen starvation of tissues occurs with a decrease in the amount of:

1) CPC, ESR
2) Leukocytes, ESR
3) Platelets, red blood cells
4) Leukocytes, erythrocytes
5) Red blood cells, hemoglobin

31. The reason for increased bleeding in diseases of the blood and hematopoietic organs:

1) destruction of the vessel wall
2) iron deficiency in the body, vascular wall changes
3) iron deficiency in the body
4) scratching, itching of the skin
5) reduction of platelets, changes in the vascular wall, changes in the coagulation system

32. Acute leukemias are not typical:

1) fever
2) the presence of skin rashes
3) hemorrhagic syndrome
4) rapid onset of the disease
5) enlargement of the liver, spleen, lymph nodes

33. What pathology leads to a lack of iron in the body:

1) Osteoporosis
2) Parkinson's disease
3) Anemia
4) Endemic goiter
5) Diabetes mellitus

34. A symptom characteristic of chronic leukemia:

1) Diarrhea
2) Belching sour
3) Burning and pain in the tongue area
4) Enlargement of the liver and spleen, lymph nodes
5) Pressure reduction

35. Name a characteristic symptom of B12 deficiency anemia:

1) Hyperemia of the skin
2) High fever
3) Burning and pain in the tongue
4) Skin maceration, pressure sores
5) Enlargement of lymph nodes

36. Care of patients with acute leukemia includes:

1) Setting up a cleansing enema
2) The use of a pocket inhaler
3) No special care required
4) Warming baths
5) Skin care, oral cavity, care for feverish patients

37. Necrotic angina is observed in patients with:

1) after bleeding
2) with iron deficiency in the body
3) with increased hemolysis
4) acute leukemia

38. Characteristics of enlarged lymph nodes in blood diseases:

1) painful, soft, the skin above them is hot, hyperemic
2) painful, dense, form packets, are suppressed
3) painless, not soldered together, movable
4) painless, dense, bumpy, immobile

39. Position of the patient during palpation of the spleen:

1) standing
2) lying on the left side
3) sitting
4) lying on the right side

40. The size of the spleen with percussion is normal:

1) 7-12*20cm
2) 4-6*6-8cm
3) 2-3*5cm
4) 3*9cm

41. Poikilocytosis is a change in red blood cells by:

1) value
2) mobility
3) form
4) coloring

42. An increase in the color index is observed in anemia:

1) hemolytic
2) B12 deficient
3) iron deficiency
4) posthemorrhagic

43. The clotting time increases when:

1) thrombocytopenia
2) insufficiency of all components of hemostasis.
3) non-sufficiency of plasma coagulation factors
4) fragility of the vascular wall

44. When diagnosing leukemia, a puncture is performed:

1) pleural
2) abdominal
3) of the spinal cord
4) sternal

45. After acute bleeding, the following laboratory parameters are the first to change:

1) Erythrocyte sedimentation rate
2) Hemoglobin and hematocrit
3) Blood formula
4) Leukocyte formula
5) Color indicator of blood

46. 1 ml of heparin contains:

1) 10000 units
2) 500 units
3) 25000 units
4) 5000 units
5) 40 units

47. When using heparin, complications may occur:

1) Air embolism
2) Necrosis
3) Thrombophlebitis
4) Oil embolism
5) Hematuria

48. Oxygen starvation of tissues occurs with a decrease in the amount of:

1) CPC, ESR
2) Platelets, red blood cells
3) Red blood cells, hemoglobin
4) Leukocytes, ESR
5) Leukocytes, erythrocytes

49. Acquired hemolytic anemia develops when

1) lung diseases
2) formation of antibodies to lymphocytes
3) the effect of hemolytic poisons
4) formation of antibodies to leukocytes
5) kidney diseases

50. What are the changes in the tongue and oral mucosa characteristic of iron deficiency anemia?

1) pronounced atrophy of the nipples of the tongue
2) the explosion of oppression
3) ulcers on the oral mucosa
4) small-point hemorrhages on the oral mucosa
5) hypertrophy and redness of the gums

51. a 42-year-old woman after examination by a doctor of the emergency department revealed lymphoproliferative syndrome. What are the most likely changes in the patient's skin color characteristic in this case?

1) alternation of redness and pallor
2) dark red shade
3) jaundice
4) hyperpigmentation
5) depigmentation

52. Which of the listed signs is most likely for the average erythrocyte hemoglobin index?

1) SLE
2) of beds
3) Hemoglobin erythrocyte saturation index
4) Ministry of Emergency Situations
5) MH

53. Which of the following causes is most likely to develop B12 deficiency anemia ?

1) infectious effects
2) poisoning with hemolytic poisons
3) castle factor deficiency
4) insufficient iron content in food
5) disorders of erythrocyte development

54. Signs of Gunther's glossitis:

1) white-yellow plaque on the tongue
2) polished, red tongue
3) pink
4) pronounced papillae on the tongue
5) teeth prints on the tongue

55. Causes of the development of anemic syndrome:

1) increased destruction of leukocytes
2) increased red blood cell production
3) heart failure
4) increased destruction of red blood cells
5) respiratory failure

56. In which syndrome of iron deficiency anemia is an increase in the liver and spleen determined, a severe form of anemia with rickets occurs:

1) epithelial
2) cardiovascular
3) astheno-vegetative
4) hepatolienal
5) of immunodeficiency

57. In which syndrome of iron deficiency anemia is characterized by dystrophy and atrophy of the mucous membranes of the skin, nails, hair?

1) epithelial
2) cardiovascular
3) astheno-vegetative
4) hepatolienal
5) of immunodeficiency

58. What kind of anemia develops as a result of excessive blood breakdown:

1) sideroachrestical
2) microspherical
3) megaloblastic
4) posthemorrhagic
5) hemolytic

59. A 47–year-old man with a history of subtotal gastric resection due to peptic ulcer disease. What kind of anemia can this person develop?

1) iron deficiency
2) hemolytic
3) chronic posthemorrhagic
4) B12 deficient
5) plastic

60. A 37-year-old woman was diagnosed with small bowel cancer. What kind of anemia can this woman develop?

1) hemolytic
2) microspherocytic
3) chronic posthemorrhagic
4) In 12 deficient
5) plastic
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